Structural formula
Business number | 01G8 |
---|---|
Molecular formula | C7H9NO2S |
Molecular weight | 171.22 |
label |
4-Toluenesulfonamide, To sulfonamide, Toluene-4-sulfonamide, Toluenesulfonamide, p-sulfonamide toluene, 4-Toluene sulfonamide, On sulfonamide, Toluene-4-sulfonamide, Toluene sulfonamide, On ammonia toluene sulfonyl, Toughening agent, aromatic sulfur compounds |
Numbering system
CAS number:70-55-3
MDL number:MFCD00011692
EINECS number:200-741-1
RTECS number:XT5075000
BRN number:472689
PubChem number:24854164
Physical property data
1. Character: White flake or leaf-like crystal
2. Density (g/mL, 25/4℃): Uncertain
3. Relative vapor density ( g/mL, air=1): Uncertain
4. Melting point (ºC): 138.5~139
5. Boiling point (ºC, normal pressure): Uncertain
6. Boiling point (ºC, 10mmHg): 221
7. Refractive index: Uncertain
8. Flash point (ºC): 202
9. Specific rotation (º): Uncertain
10. Autoignition point or ignition temperature (ºC): Uncertain
11. Vapor pressure (kPa, 25ºC): Uncertain
12. Saturated vapor pressure (kPa, 60ºC): Uncertain
13. Heat of combustion (KJ/mol): Uncertain
14. Critical temperature (ºC): Uncertain
15. Critical pressure (KPa): Uncertain
16 . The logarithmic value of the oil-water (octanol/water) partition coefficient: Uncertain
17. Explosion upper limit (%, V/V): Uncertain
18. Explosion lower limit (% ,V/V): Uncertain
19. Solubility: Soluble in ethanol, insoluble in water (0.32 g/100 mL, 25 º C) and ether.
Toxicological data
Acute toxicity: mouse intraperitoneal LC50: 250 mg/kg; subcutaneous injection of LDLo in guinea pigs: 2 mg/kg; oral LD50 of wild birds: 75 mg/kg; mutagenicity: Salmonella microbial changes test system: 40 umol/plate;
Ecological data
None
Molecular structure data
1. Molar refractive index: 43.81
2. Molar volume (cm3/mol): 134.6
3. Isotonic specific volume (90.2K ): 351.2
4. Surface tension (dyne/cm): 46.3
5. Polarizability (10-24cm3): 17.36
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 1
3. Number of hydrogen bond acceptors: 3
4. Number of rotatable chemical bonds: 1
5. Number of tautomers: none
6. Topological molecule polar surface area 68.5
7. Number of heavy atoms: 11
8. Surface charge: 0
9. Complexity: 209
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
Storage method
1. Packed in an inner plastic bag, an outer woven bag or an inner plastic bag, a middle layer of kraft paper bag, and an outer woven bag. Handle it with care during storage and transportation, and protect it from moisture and heat. Store and transport according to regulations for flammable and toxic substances. 2. This product should be stored in a sealed, cool and dry place.
Synthesis method
1. Obtained from the reaction of p-toluenesulfonyl chloride and ammonia.
Purpose
1. Used in organic synthesis. p-Toluenesulfonamide is mainly used in the synthesis of chloramine-T and chloramphenicol (Tevenel). 2. Used for synthesizing fluorescent dyes, manufacturing plasticizers, synthetic resins, coatings, disinfectants and wood processing brighteners, etc. 3. Mainly used as a toughening agent for the synthesis of water-soluble melamine formaldehyde resin. 4.Used as primary brightener in bright nickel plating. Used for bright multi-layer nickel plating to make the coating bright and uniform. The general dosage is 0.2~0.3g/L.
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